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Image #   291002C
Name:   Clostridium spore development
Copyright:   Copyright 2010 Dennis Kunkel Microscopy, Inc.
Description:   Caption: Clostridium spore formation and developmental stages - vegetative cell (left) to mature spore forming cell with large spore (right). Clostridium spp. are Gram-positive, endospore-forming, anaerobic, rod prokaryotes that occur in many environments. In their vegetative stage they rapidly undergo division and retain their thin, rod-shaped (bacillus) appearance. When environmental conditions become less favorable for normal growth the vegetative cells will to form a spore (endospore) inside the cell. The primary function of most endospores is to ensure the survival of a bacterium through periods of environmental stress. Spores can remain viable for many years and will start to grow when more favorable growth conditions occur. Important Clostridium species include: Clostridium botulinum causes food poisoning (botulism), wound infections and infant botulism. Clostridium difficile is a spore-forming bacteria that is a normal part of the intestinal flora, especially in young children. It is the major cause of pseudomembranous colitis and antibiotic produced diarrhea. It produces 2 toxins, which cause inflammation of the intestinal wall (colitis) along with diarrhea, abdominal pain and fever. It is one of the most common hospital (nosocomial) infections around the world. Clostridium sporogenes is widely distributed in nature and also in the intestines of animals. This bacterium frequently occurs in the intestines of humans and many domestic and feral animals. It can lead to gaseous gangrene in humans. Spores persist in soil and areas subject to human or animal fecal pollution.
Magnification*: x2,500
Type: SEM
    *(Magnifications are based on a 35mm slide image of 24mm in the narrow dimension.)
Keywords:   291002C 03.01.10 bacilli bacillus bacteria bacterial pathogen bacterium botulism Clostridium botulinum endospore forming food poisoning Gram-postive Gram positive human disease infant botulism prokaryote rod spore vegetative wound infection SEM intestine infection food spoilage abdominal pain anaerobe anaerobic antibiotic-associated diarrhea antibiotic-resistant antibiotic associated diarrhea antibiotic resistance anticlostridial antibiotic anticlostridial antibiotics bacteria toxin bacteria toxins bacterial toxin clostridia Clostridium difficile diarrhea endospore endospore-forming fever flagella flagellum gastrointestinal infection Gram-positive hospital infection human infection human pathogen intestinal flora intestinal infection intestinal tract intestine flora metronidazole motile nosocomial infection psuedomembranous colitis rod-shaped rod shaped rod shaped bacteria soil bacteria soil bacterium soil microbe soil organism spore-forming spore forming bacterial Clostridium Clostridium sporogenes prokaryotes endopores vegetative cell intestinal bacteria intestinal bacterium intestinal spore intestinal spores intestine bacterium intestine bacteria gastrointestinal bacteria gastrointestinal bacterium intestine microbe intestine microbes soil microorganism soil microorganisms soil microbes soil micro-organism gaseous gangrene gangrene gangrene infection infection gas gangrene binary fission dividing dividing bacteria dividing bacterium division Clostridium endospore formation Clostridium spore Clostridium spore formation Clostridium spores endospore formation spore formation antibiotic resistant bacteria endospore bacteria endospores bacterial endospore bacterial endospores bacterial spore bacterial spores vegetative cells vegetative stage

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