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Image #   28908B
Name:   Differentiating stem cell from cord blood
Copyright:   Copyright 2008 Dennis Kunkel Microscopy, Inc.
Description:   Caption: Differentiating stem cell (CD34+) from umbilical cord blood. Shown here is the first stage of a CD34+ stem cell differentiating in to another blood cell type. Note the new protoplasmic bulge forming at one position on the CD34+ stem cell periphery; this new growth extension of the cell is the first morphological sign of the stem cell developing in to another cell type. CD34+ stem cells are normally found in the umbilical cord and bone marrow as hematopoietic stem cells. CD34+ stem cells are multipotent because they differentiate to produce precursor (progenitor) cells of any of the body's blood cell types. This process of stem cell differentiation in the circulatory system is called hemopoiesis. Hematopoietic stem cells develop either into red blood cells, or one of several types of white blood cells that make up the immune system. Blood cells have short life spans and are therefore constantly produced by the bone marrow. There are three main types of mammalian stem cells: embryonic stem cells, derived from blastocysts; adult stem cells, which are found in some adult tissues; and cord blood stem cells, which are found in the umbilical cord. The purification and isolation of stem cells from umbilical cord blood allows scientists to research the function of the immune system and to develop treatments for diseases such as AIDS, leukemia and other immune diseases. CD34 is a cluster differentiation molecule present on undifferentiated stem cells within the human body. It is a cell surface glycoprotein and functions as a cell-cell adhesion factor. As these cells begin to develop as distinct cell lineages the cell surface markers are no longer identified.
Magnification*: x2,600
Type: SEM
    *(Magnifications are based on a 35mm slide image of 24mm in the narrow dimension.)
Keywords:   28908B 12.01.08 cd34 positive cd34+ stem cell stem cells foetal stem cell foetal cd34 stem cell fetal stem cell fetal cd34 stem cell fetal cd34 stem cells foetal stem cells foetal cd34 stem cells fetal stem cells fetus stem cell fetus cd34 stem cell fetus cd34 stem cells fetus stem cells haemopoiesis medical multipotent stem cell multipotent stem cells multipotent cd34 stem cell multipotent cd34 stem cells stem cell research umbilical cord umbilical cord blood cord blood cord blood cell cord blood cells cord blood stem cell cord stem cell cord stem cells SEM hematopoietic stem cell hematopoietic stem cells hematopoietic progenitor cell progenitor cells precursor cell precursor cells haematopoietic stem cell haematopoietic stem cells haematopoietic red blood cell precursor red blood cell progenitor red blood cells red blood cell precursors red blood cell progenitors human blood human red blood cell human red blood cells immune system immune system development erythrocyte erythrocytes leukocyte leukocytes red blood cell development white blood cell development blood cell development AIDS leukemia immune disease immune diseases isolated stem cell isolated stem cells fetal cord blood fetus cord blood foetal cord blood baby blood blood differentiate blood differentiation bone marrow stem cell differentiation circulatory system blood system stem cell development mammalian stem cell mammalian stem cells embryonic stem cells embryonic stem cell adult stem cell adult stem cells blastocyte blastocytes diverse cell type diverse cell types esc haematology hematology hemopoiesis hsc hscs multipotent multipotential pluripotent pluripotential undifferentiated undifferentiated stem cell undifferentiated stem cells unspecialized stem cell unspecialized stem cells somatic stem cell somatic stem cells cell to cell adhesion factor glycoprotein glycoproteins cell-cell adhesion factor stem cell growth blood forming stem cell blood-forming stem cell hematopoietic stem cell differentiation human stem cell human stem cells blood-forming stem cells blood forming stem cells white blood cell white blood cells differentiating stem cell differentiating stem cells differentiating CD34 stem cell differentiating CD34 stem cells human adult stem cell human adult stem cells

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